YHU Scientific Journal, Vol 11, p34-46, 2024
ANALYSIS OF THE STABILITY DATA OF "HEPARIN SODIUM SALT 5000 IU/ML" SO-LUTION DURING THE REGISTRATION PROCESS OF THE DRUG
V.Khazoyan, H.Grigpryan
Yerevan Haybusak University
Submitted 02.06 , Accepted 17.07
DOI: 10.61484/29538181-sj.11.24-3
Abstract. The study of drug stability provides an opportunity to understand the shelf life of the drug, which is the basis for understanding the optimal amount and method of primary pack-aging during drug production, as well as production volumes based on market demand. Various dosage forms of Heparin are known, such as injection solutions, gels for exter-nal use, and creams. Heparin, as a rule, is not available in the form of dosage forms for in-ternal administration (tablets, capsules, solutions for internal administration, etc.), because it is not absorbed during internal administration, mainly due to the large size of the molecule and the polyanionic charge. Studying of stability data of “Heparin sodium salt 5000 IU/ml” solution during the drug registration process is important because in Armenia this dosage form is the most registered in quantity and, therefore, the most used by the population, based on which it is important to understand which data indicate the quality of the drug.
Keywords: Diabetes, heparin, sodium salt, pill, quality, stability
Abstract. The study of drug stability provides an opportunity to understand the shelf life of the drug, which is the basis for understanding the optimal amount and method of primary pack-aging during drug production, as well as production volumes based on market demand. Various dosage forms of Heparin are known, such as injection solutions, gels for exter-nal use, and creams. Heparin, as a rule, is not available in the form of dosage forms for in-ternal administration (tablets, capsules, solutions for internal administration, etc.), because it is not absorbed during internal administration, mainly due to the large size of the molecule and the polyanionic charge. Studying of stability data of “Heparin sodium salt 5000 IU/ml” solution during the drug registration process is important because in Armenia this dosage form is the most registered in quantity and, therefore, the most used by the population, based on which it is important to understand which data indicate the quality of the drug.
Keywords: Diabetes, heparin, sodium salt, pill, quality, stability